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Bone Anatomy

From the ends of the bone inward is the:
  • Epiphysis,
    • It provides the cap to the bone and is covered in articular cartilage for the joint space.
  • Epiphyseal plate (aka the growth plate or physis)
    • When the growth plate closes it forms the epiphyseal line.
    • This separates the epiphysis and the metaphysis.
  • Metaphysis
  • Diaphysis
    • This is the bone shaft. It contains the medullary (marrow) cavity.
collagenous structures
  • Articular cartilage is derived from hyaline cartilage, at its ends.
  • Periosteum, along the shaft, is derived from a condensation of outer connective tissue.
    • It comprises an external layer of collagens fibers and vasculature and an internal layer of osteoprogenitor cells.
  • Endosteum, centrally, is derived from derived from a condensation of inner connective tissue and helps separate the marrow cavity, internally, from the compact bony matrix that encapsulates it.
    • It comprises an inner parallel-layered lamellae and osteoprogenitor cells.
marrow cavity
  • Filled with hematopoetic marrow (red blood cell and white blood cell precursors) and fatty marrow (adipose tissue).
    • It comprises stem cells, which can self-renew, committed precursor cells, and cells that are in the process of maturation.
Bone Tissues
  • Compact bone forms the outer layer of bone.
  • Spongy bone forms the inner mass of bone.
    • It comprises a network of lamellae that do NOT form the Haversian channels and osteons found in compact bone.
  • The marrow cavity forms within the center of bone.