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Rotation of the Pancreatic & Biliary Ducts

final arrangement of the biliary and pancreatic ducts
In two diagrams.
Top Diagram
  • The abdominal accessory digestive organs arise as outgrowths of the foregut, prior to stomach and duodenal rotation.
    • The dorsal pancreatic bud extends dorsally.
    • The ventral pancreatic bud, gallbladder, and liver buds (aka, hepatic diverticulum) extend ventrally.
    • The liver buds develop as an outgrowth of the foregut into the septum transversum.
The connection between the liver buds and foregut narrows to form the bile duct; the bile duct then gives rise to its own outgrowth, which becomes the gallbladder and cystic duct.
  • The proximal duodenum rotates clockwise.
Bottom Diagram
By week 11, rotation is complete, and the organs are in their final locations.
  • The ventral and dorsal pancreatic buds and their ducts fuse.
    • The complete pancreas nestles into the c-curve of the duodenum and extends towards the left side of the body.
    • The uncinate process is the portion derived from the ventral pancreatic bud.
    • The main pancreatic duct, which drains smaller ducts and empties into the duodenum via the major papilla.
    • The accessory pancreatic duct drains via the minor papilla. In many individuals, this structure degenerates and is absent in the adult.
  • The bile and pancreatic ducts join to drain bile and pancreatic juices at the major papilla.
    • The liver drains bile into the hepatic duct.
    • The gallbladder drains bile into the cystic duct;
    • The hepatic and cystic ducts merge to form the common bile duct.
    • Because of the rotation of the foregut and the displacement of the papillae, the common bile duct wraps posteriorly around the duodenum;
    • It joins with the main pancreatic duct to drain bile at the major papilla to the duodenum.
    • Thus, the major papilla provides an entryway for both bile and pancreatic juices.