Features
- Hydrocephalic 3rd ventricle, Enlarged diencephalon, and Dysgenic corpus callosum... much like in the Chiari Type 2.
- Cerebellar vermis agenesis and a grossly dilated, cystic 4th ventricle.
Hindbrain Malformation: Dandy Walker Malformation
Pathologic/Radiographic Features
- Hydrocephalic 3rd ventricle
- Enlarged diencephalon
- Dysgenic corpus callosum (much like in the Chiari Type 2).
- Cerebellar vermis agenesis
- Grossly dilated, cystic 4th ventricle
Clinical Manifestations
- Impaired motor development
- Macrocephaly (enlargement of the skull)
Association with Additional Syndromes (eg, Walker Warburg syndrome)
- Dandy Walker malformation can be associated with other syndromes such as Walker Warburg syndrome or other syndromes involving cardiac, neural, and limb developmental anomalies.
- Walker Warburg syndrome combines a Type 2 Lissencephaly with Dandy Walker malformation.