Development of the Vulva

embryology of the female external genitalia
Aka, the vulva
During gestation, development is influenced by estrogen from the placenta, and, possibly, the developing fetal ovaries.
Weeks 3-4
Undifferentiated primordial genitalia
During weeks 3-4 the genital tubercle, which is the precursor to the clitoris, emerges.
  • Recall that the cloacal membrane covers the opening of the cloaca prior to separation of the distal urinary and digestive tracts.
  • Primordia of the genital tubercle borders the membrane.
  • Anterior fusion of the primordia forms the definitive genital tubercle.
  • Posteriorly, the unfused portion gives rise to the genital (aka, urogenital) folds, which enclose the cloacal membrane.
  • Lateral to the folds the genital swellings (aka, labioscrotal swellings) take form.
Weeks 7-9
Elongation of the urorectal septum divided the cloaca into urogenital and digestive tracts.
  • By this stage, the genital tubercle and folds are enlarged.
  • Perineal body lies posterior to the genital folds
    • Perineal body is where the urorectal septum connected to the cloacal membrane, it separates the genital folds from the anal folds.
    • Aka, the central tendon of the perineum
  • Division of the cloacal membrane gives rise to the urogenital membrane, enclosed by the genital folds, and, the anal membrane, enclosed by the anal folds.
  • By the end of week nine, the urogenital and anal membranes disappear.
  • Genital tubercle is now the glans of the clitoris.
  • Urogenital groove appears where urogenital membrane was.
  • Anus appears where the anal membrane was.
  • The area between the urogenital groove and anus is the perineum.
Weeks 11-12
Final stages of vulva formation.
  • Glans of the clitoris recedes.
  • The genital folds give rise to the labia minora
    • Prepuce of labia minora covers body of clitoris
    • Vestibule of vagina is area between right and left labia minora; urethra and vagina open to vestibule.
  • The genital swellings give rise to the labia majora
    • Anterior fusion = mons pubis
    • Posterior fusion = posterior labial commissure
  • Deeper structures
Clitoris
    • Glans
    • Body
    • Crus
Bulb of the vestibule
    • Deep to clitoral crura and vestibule of the vagina.