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Voltage-gated Ion Channels
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Voltage-gated Ion Channels

a) Sodium Channel
  • Change in membrane potential opens the channel – activation gates change to the open conformation and sodium can traverse the membrane
  • Channel becomes inactivated – Inactivation gate "plugs" the channel and sodium cannot travel through the membrane
  • Channel eventually resets back to closed conformation
b) Potassium channel
  • Change in membrane potential opens the channel – activation gates change to the open conformation and potassium can traverse the membrane
  • Channel eventually resets back to closed conformation

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