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Cancer Causing Mutations
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Cancer Causing Mutations

CANCER
  • Cells reproduce in defiance of restraints
  • Cells invade and colonize territories reserved for other cells
Benign tumors
Reproduce without restraint but are noninvasive
Malignant tumors
Reproduce and metastasize
Proto-oncogene
Gene whose protein product stimulates normal cell growth and division
Oncogene
Mutated gene that has hyperactive function that can lead to cancer
Tumor suppressor gene
Gene whose protein product inhibits cell division and whose mutation can lead to cancer if it leads to decreased function
4 TYPES OF CANCER CAUSING MUTATIONS
Proto-oncogene
1) Gene moves to new location
  • Could lead to excess protein production
2) Gene is duplicated
  • Could lead to excess protein production
3) Mutation in gene's control element
  • Could lead to excess protein production
4) Mutation in gene itself
  • Could lead to hyperactive or degradation resistant protein

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