GENE EXPRESSION REGULATION OVERVIEW
- Allows organisms to be more efficient with resources and to adapt to the environment
- Important for cell differentiation (which results in many different cell types)
STEPS REGULATION OCCURS
1)
Transcriptional Control
- When and how often a gene is transcribed
- Only point where the cell will not synthesize unneeded intermediates, thereby wasting resources
2) RNA Processing Control
- Control of the splicing and processing of RNA transcripts
3) RNA Transport and Localization Control
- Cells select which mRNAs are exported to the cytoplasm and where they are localized to
4)
Translational Control
- Control which mRNAs get translated into protein
5) mRNA Degradation Control
- Cells can destabilize specific mRNAs in the cytoplasm to limit protein production
6) Protein Activity Control
- Cells can selectively activate, inactivate, localize or degrade proteins after they have been synthesized