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Enzymology: 1. Overview
Energy Diagram
Calculation of DELTA G
We calculate DELTA* G as the: – Free energy of the product minus the free energy of the reactants. – Thus, DELTA G is a negative value for a spontaneous reaction. – It is also an exergonic reaction, because energy is released.

Enzymology: 1. Overview

key features of enzymes
  • Enzymes are biological catalysts that increase the rate of reaction by lowering activation energy.
  • Enzymes catalyze the conversion of a substance called a substrate, to another substance, called a product.
  • Enzymes act on a substrate to speed up the rate of creation of the product.
  • Most enzymes are proteins, although RNA enzymes also exist.
– This means that the same physiological conditions that affect proteins also affect enzymes.
  • Enzymes are specific: any given enzyme will catalyze the conversion of a specific substrate to a specific product.
  • Enzymes may require other organic or inorganic molecules, called coenzymes or cofactors, to enhance their activity.
  • Enzyme activity is carefully regulated within the cell to control the rates of enzyme-catalyzed reactions.