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Sulfhydryl (Thiol)
Sulfhydryl group (Thiols)
  • We connect an R to an SH.
Sulhydryls are also known as thiols, and are the sulfur analogs of alcohols.
Sulfhydrl groups are integral to enzyme function; they are in enzyme active sites and contribute to catalytic activity.
They are part of many cofactors, including coenzyme A, which is important in fatty acid biosynthesis and the Krebs cycle.

Sulfhydryl (Thiol)

Sulfhydryl Functional Group
  • Structure: an R connected to an SH.
  • Also known as thiols
    • the sulfur analogs of alcohols.
  • Sulfhydrl groups are integral to enzyme function; they are in enzyme active sites and contribute to catalytic activity.
  • Thiols are part of many cofactors, including coenzyme A, which is important in fatty acid biosynthesis and the Krebs cycle.
  • Two sulfhydryl groups may react to form disulfide linkages

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