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Disaccharides

DISACCHARIDES
Summary
COMMON DISACCHARIDES
  • Commonly dietary
  • Made of 2 monosaccharides joined by O-glycosidic bond
  • Formed by condensation reaction between –OH groups
  • General formula: C12H22O11
Sucrose
  • Glucose + fructose
  • alpha-1,2-glycosidic bond: C1 –OH (alpha-D-glucose) + C2 –OH (beta-D-fructose)
  • Common table sugar
  • Sucrase: cleaves sucrose into monosaccharides
Maltose
  • Glucose + glucose
  • Alpha-1,4-glycosidic bond: C1 –OH (alpha-D-glucose) + C4 –OH (alpha-D-glucose)
  • Product of starch/glycogen/large oligosaccharide hydrolysis
  • Maltase: cleaves maltose into monosaccharides
Lactose
  • Galactose + glucose
  • Beta-1,4-glycosidic bond: C1 –OH (beta-D-galactose) + C4 –OH (alpha-D-glucose)
  • Disaccharide in milk
  • Lactase (humans)/beta-galactosidase (bacteria): hydrolyze lactase into monosaccharides

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